This report aims to collect, analyze and disseminate the knowledge base for practitioners and policymakers on tools, key strategies and good practices on integrated ecosystem management in connection with livelihoods in transboundary landscapes of the Lancang-Mekong region to enhance knowledge on the value of ecosystem management, promote integrated management of key ecosystems and contribute to South-South learning. In particular, it allows readers to understand what possible tools for transboundary landscape management are, where the major transboundary landscapes are in the Lancang-Mekong region, how these are defined and established, what key challenges are to be addressed in these landscapes and what has already been done to address these challenges. Several best practice examples from different transboundary parts of the region and ecosystem types are also provided to show how transboundary management actions have been carried out.